Winter Seminar Series - Dr. Isaac Chui, Harvard Medical School
Molecular Genetics Colloquium MMG1003H: Winter 2024 Seminar Series
Dr. Isaac Chui, Harvard Medical School
Title: Neuronal regulation of barrier immunity and host defense
Date: Monday, February 12th, 2024
Time: 3:00 PM - 4:00 PM EST
Location: MSB 3153
Host: Dr. Julie Lefebvre
Talk Abstract:
Neuroimmune interactions play a critical role in regulating homeostasis and host defense. Barrier tissue sites are densely innervated by sensory neurons that mediate pain and itch. We and others have found that these neurons directly sense microbial pathogens and their mediators including toxins and enzymes. They then release neuropeptides and other mediators that signal to immune cells to regulate their function. Microbes also in some instances hijack these neuroimmune interactions for their advantage. Therefore, understanding how neurons interact with microbes and immune cells can lead to novel understanding of host defense and barrier immunity.
Research Topic: Immune-neuron Interactions; Mouse Models.
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