Peter Gilgan Centre for Research and Learning
686 Bay Street, 14-9714, Toronto, Ontario Canada M5G 0A4
- Understand DNA repeat instability; the cause of >40 diseases including Huntington's disease, muscular dystrophy & amyotrophic lateral sclerosis.
- Use molecular, stem cell, transgenic mouse models and human tissues to understand and modulate this mutation for clinical benefit.
- Focus on DNA repair, replication & epigenetics.
- Identify therapeutic targets and preclinical therapeutic drugs.