We are a computational biology lab focusing on systems biology at the cell and tissue level. We have made many contributions to network and pathway analysis and interpretation of genomics data to support biological discovery and precision medicine applications. More recently we are developing computational methods and an ecosystem theory of tissue function that considers cell-cell interactions, cell growth, and cell internal mechanisms, such as pathways, reactions, and causal relationships, to help understand development, cancer and regenerative wound healing processes.
- The Lunenfeld-Tanenbaum Research Institute at Sinai Health System
- Princess Margaret Cancer Centre at University Health Network
- Department of Computer Science, University of Toronto
- Donnelly Centre