James Dowling

Molecular Genetics


SickKids - Peter Gilgan Centre for Research and Learning
686 Bay Street, 15-9703, Toronto, Ontario Canada M5G 0A4
Research Interests
Disease models, Drug discovery, design, development and screening, Rare diseases, Zebrafish

My laboratory seeks to understand the pathogenic mechanisms of and develop therapies for childhood muscle diseases.  We combine gene discovery and model systems research to define disease pathology and identify treatments. Our favourite model system is the zebrafish, and we are interested in the role of endolysosomes in muscle biology.