Julie M. Claycomb

Molecular Genetics


MaRS West Tower
661 University Avenue, Room 1535, Toronto, Ontario Canada M5G 1M1
Research Interests
Bioinformatics and computational biology, C. elegans, Developmental biology, Epigenetics and epigenomics, Functional genomics and systems biology, Gene regulation and expression, Genome analysis and sequencing, Non-coding DNA and RNA, Imaging and microscopy, Protein-protein, DNA-protein, and RNA-protein interactions, Translation and post-transcriptional regulation
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Our research is aimed at uncovering the molecular mechanisms by which small RNA pathways related to microRNAs and RNA interference regulate gene expression throughout animal development. We are currently interested in understanding the tissue-specific functions of small RNA pathways, learning how small RNA pathways in the germline contribute to fertility and transgenerational epigenetic inheritance, and uncovering how small RNAs can be used to communicate between tissues and organisms. Our studies exploit integrated experimental approaches including molecular genetics, genomics, and cell biology in the model nematode and champion of small RNA biology, C. elegans.

Courses taught

  • MGY311: Molecular Biology


  • Canada Research Chair Tier II in Small RNA Biology
  • Associate Editor, GENETICS
  • University of Toronto Faculty of Medicine Graduate Early Career Teaching and Mentorship Award
  • University of Toronto Mid-Career Faculty of Medicine Graduate Teaching and Mentorship Award
  • Ontario Early Researcher Award (2014-2019)

Twitter accounts 

Student group mentorship

  • Toronto RNA Club
  • Toronto RNA Enthusiasts' Day groups