William Navarre

Molecular Genetics


MaRS West Tower
661 University Avenue, Room 1635, Toronto, Ontario Canada M5G 1M1
Research Interests
Bacterial and fungal pathogens, Bioinformatics and computational biology, Disease models, Evolution and phylogenetics, Functional genomics and systems biology, Gene regulation and expression, Mouse models, Infectious disease and microbiology, Immunology, Microbiome, Metabolism, Protein-protein, DNA-protein, and RNA-protein interactions, Technology development

The Navarre lab focuses on the endogenous microbes (microbiota) of animals, with a particular focus on the microbes of laboratory mice. Laboratory mice are the primary animal model system for nutritional science, physiology, pharmacology, cancer biology, behaviour, and immunology. Recently it has become clear that differences in the microbes among different lines of mice are a source of experimental irreproducibility. The Navarre lab aims to collect and study the microbes associated with mice and collaborate with others to explain how different microbes affect the outcomes of diseases like inflammation, cancer, and diabetes. The Navarre lab has cultivated an extensive collection of unique and rare bacteria associated with mice that have intestinal inflammation. We are determining the properties of these microbes to explain how they thrive in an inflamed environment and how they might contribute to exacerbating or resolving disease.

Courses taught

  • MGY277 - Introduction to Medical Microbiology
  • MGY377 - Microbiology I: Bacteria