Faculty Candidate Seminar: Coral Zhou, University of California, Berkeley
Candidate for Assistant Professor, Molecular Biology & Genetics
Coral Zhou, PhD Postdoctoral Fellow, University of California, Berkeley
Date: Thursday, May 9, 2024 2:00 p.m.
Location: Red Seminar Room, Donnelly CCBR
Mechanisms of genome scaling during embryogenesis and evolution
Across the tree of life, genome size scales with nuclear size and cell size, yet underlying mechanisms are largely unknown. Using a combination of in vitro and in vivo approaches unique to the African clawed frog Xenopus laevis, we recently discovered the molecular mechanisms underlying how mitotic chromosomes scale in size during the rapid and reductive cell divisions in the early embryo. We are currently expanding our toolkit to study mechanisms of genome scaling across multiple spatial scales of chromatin organization and in the context of early vertebrate development, evolution and disease.