Lunenfeld-Tanenbaum Research Institute
600 University Avenue, Room 1084, Toronto, Ontario Canada M5G 1X5
Cancer, CRISPR-Cas9 and genome engineering, Disease models, Functional genomics and systems biology, Mouse models, Single cell and spatial biology, Stem cell biology
Our research focuses on leveraging functional genomics to make major advances in treating human cancers in a personalized and highly specific manner. Our goal is to find novel therapies to combat the most devastating malignancies by systematically screening for genotype-specific cancer vulnerabilities. We, therefore, develop direct in vivo gene-editing tools to integrate human cancer genomics and mouse modelling to functionally assess the tumorigenic and metastatic capabilities of hundreds of putative cancer genes.
- Cancer Genetics
- Canadian Research Chair in Functional Cancer Genomics
- Lunenfeld-Tanenbaum Research Institute