Our research focuses on leveraging functional genomics to make major advances in treating human cancers in a personalized and highly specific manner. Our goal is to find novel therapies to combat the most devastating malignancies by systematically screening for genotype-specific cancer vulnerabilities. We, therefore, develop direct in vivo gene-editing tools to integrate human cancer genomics and mouse modelling to functionally assess the tumorigenic and metastatic capabilities of hundreds of putative cancer genes.
- Cancer Genetics
- Canadian Research Chair in Functional Cancer Genomics
- Lunenfeld-Tanenbaum Research Institute