Professor
James Dennis
Molecular Genetics
PhD
Location
Lunenfeld-Tanenbaum Research Institute
Address
600 University Avenue, Room 988, Toronto, Ontario Canada M5G 1X5
Research Interests
Cancer, Cell biology, Evolution and phylogenetics, Mouse models, Immunology, Metabolism, Signalling
Category
Cellular and Molecular Structure and Function, Computational and Systems Biology, Genetic Models of Development and Disease
We study the role of nutrient transporters, in signalling and metabolic homeostasis. The surface expression of many amino acids transporters is dependent on N-glycosylation in the ER and modifications in the Golgi and plays a role in inflammation and cancer. Methods include genetic modification by CRISPR/Cas and proteomics using cultured cells and mice.
Courses
- MMG1041: Cell Cycle & Growth Control
- MMG1011: Small Group Seminars
Cross-affiliations
- Lunenfeld Tanenbaum Research Institute