MaRS West Tower
661 University Avenue, Room 1633, Toronto, Ontario Canada M5G 1M1
Cancer, Cell biology, CRISPR-Cas9 and genome engineering, Gene regulation and expression, Imaging and microscopy, Protein-protein, DNA-protein, and RNA-protein interactions, Proteomics and proteins, Translation and post-transcriptional regulation, Viruses
My lab is interested in the Epstein-Barr virus (EBV) and how it carries out life-long infections, subverts host antiviral responses and promotes oncogenesis. We use proteomics methods to discover 1) the roles of the many (~80) EBV encoded proteins in manipulating cellular processes to promote cell survival and infection, 2) cellular proteins that restrict EBV infection and 3) the role of SUMO modifications in regulating viral infections.
- Tier 1 Canada Research Chair in Molecular Virology (2004-2018)