Associate Professor

Tae-Hee Kim

Molecular Genetics


SickKids - Peter Gilgan Centre for Research and Learning
686 Bay Street, 16-9709, Toronto, Ontario Canada M5G 0A4
Research Interests
Cancer, Cell biology, Disease models, Epigenetics and epigenomics, Gene regulation and expression, Mouse models, Intestinal health, Microbiome, Regenerative medicine and tissue engineering, Signalling, Single cell and spatial biology, Stem cell biology

We are interested in the mechanisms of the stem cell microenvironment and its perturbation in diseases such as inflammation and cancer. Using the gut as a model system and applying mouse genetics, epigenomics and gut organoid cultures, we investigate signalling, chromatin modification and the transcriptional basis of gastrointestinal stem cell niches.

Courses taught

  • Molecular Genetics Colloquium
  • Molecular Genetics Topic Course
  • Stem Cell II PSL1014S The Gastrointestinal Epithelium


  • 2011: North American NeuroEndocrine Tumor Society Early Career Development Award
  • 2012: NIH Pathway to Independence Award (K99/R00)
  • 2014: Catalyst Scholar in Regenerative Medicine
  • 2016: March of Dimes Basil O'Connor Starter Scholar Research Award
  • 2018: Conquer Cancer Now Award, Concern Foundation
  • 2020: The Litwin IBD Pioneers Research Award (co-PI, Dr. Keith Pardee)


  • Developmental and Stem Cell Biology Program at The Hospital for Sick Children