New Zinc Finger Model Shows Promise for Gene Therapy
MoGen labs collaborate for new study published in Nature
Dr. Philip Kim and Osama Abdin, co-authors of the new study on Zinc finger proteins
MoGen researchers developed a novel technology that can engineer proteins to target any stretch of DNA in the human genome, opening a door toward gene therapies for a broader range of health conditions.
The researchers, foremost Osama Abdin from the lab of Prof. Philip Kim, fed data from billions of interactions between zinc finger proteins and DNA into a machine-learning model, which can then generate engineered zinc fingers that bind to any given sequence of DNA. The group worked with MoGen Professors Tim Hughes and Mikko Taipale, other University of Toronto labs and researchers from New York University, and the study is published in Nature.
