Curriculum

This course is an introduction to computational methods and resources for processing data from high throughput molecular biology experiments. The course focuses on the analysis of 'omics data with an emphasis on genome and transcriptome sequencing data. Major topics include sequence alignment, differential expression testing and genome annotation and interpretation. Assignments focus on hands-on skill development using the R programming language and modern bioinformatics practices such as software version control and reproducibility.

Course Coordinator: Dr. Jared Simpson

Syllabus

How is the genome of a single cell able to program the development of complex organisms such as ourselves? Model systems such as the nematode worm, fruit fly, zebrafish, laboratory mouse and pluripotent stem cells have provided most of the answers. Classic forward and reverse genetic approaches used to unveil these processes are discussed. Validated molecular mechanisms governing key spatial and temporal events are explained. Knowledge gained from these experimental models has informed much of our understanding of the genetics of human development and disease.

Course Coordinator: Dr. Stephanie Protze

Syllabus

This course explores current topics in human and molecular genetics, with a focus on the genetic basis of health and disease. Key areas include chromosome structure and function, inheritance patterns of mutations and genetic disorders, the organization and analysis of the human genome, and strategies for disease gene mapping. Additional topics cover the genetics of cancer, gene-based diagnostics and therapeutic approaches, and the use of animal models to study human diseases. As a survey course, this class introduces students to a curated selection of representative themes and emerging issues across the field, offering breadth of perspective rather than exhaustive detail. Lectures are delivered by experts in diverse areas of genetic disease, allowing students to gain exposure to multiple approaches and viewpoints. For this reason, a solid foundation in basic genetics, molecular biology, and genomics is expected.

Course Coordinators: Dr. Michael Wilson and Dr. Sagi Abelson

Syllabus

An opportunity for specialized individual research for 4th-year students in Molecular Genetics and Microbiology by arrangement with the course coordinator.  Students with an interest in graduate research are encouraged to participate.

Enrolment process:

After securing a supervisor, students must submit their enrolment request to the course coordinator. Once approved, students will be enrolled in MGY480Y1 by the Undergraduate Program Coordinator. Students cannot enroll directly through ACORN.

Course Coordinator: Dr. Marc Meneghini

Syllabus

Analysis of the strategies used by pathogenic microbes to evade specific and innate immune responses, and the strategies used to combat infectious disease using vaccines, with an emphasis on molecular and immunological aspects. Special topics include: molecular basis of pathogenicity and immune-evasion strategies; vaccination strategies; challenges to vaccine implementation (given jointly by the Departments of Molecular Genetics and Immunology).

Course Coordinator: Dr. Scott Gray-Owen

Syllabus

Taught by the Department of Molecular Genetics and delivered by the School of Continuing Studies to students who are not enrolled at U of T.  Currently enrolled U of T students should take the similar course, MGY277H1. This course will cover the basics of medical microbiology for students wishing to pursue studies in professional schools like nursing, dentistry, or medicine.

For more information, please visit the School of Continuing Studies' website.