Assistant Professor
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Assistant Professor
Ashish Deshwar
Department of Molecular Genetics - Department of Paediatrics
MD, PhD
Location
SickKids - Peter Gilgan Centre for Research and Learning
Address
686 Bay Street, M5G 0A4, Toronto, Ontario Canada M5G 0A4
Research Interests
CRISPR-Cas9 and genome engineering, Developmental biology, Disease models, Rare diseases, Stem cell biology, Zebrafish
Clinical Interests
crispr-cas9
The Deshwar lab’s overall theme is centered around exploiting the spontaneous variation seen in rare genetic diseases for the advancement of human health. This includes the study of rare genetic liver disorders with the aim of identifying both mechanisms of disease and therapeutic strategies that can be applied to the broader population. The lab’s other primary areas of interest are in leveraging disease models for the discovery of novel genetic disorders and expanding the diagnostic tool kit for genetic disease. The Deshwar lab utilizes both the zebrafish model system and human iPSC derived cells as complementary in vivo and in vitro systems respectively.