Associate Professor
Craig Smibert
Molecular Genetics
PhD
Location
MaRS West Tower
Address
661 University Avenue, Room 1537, Toronto, Ontario Canada M5G 1M1
Research Interests
Developmental biology, Drosophila, Gene regulation and expression, Non-coding DNA and RNA, Protein-protein, DNA-protein, and RNA-protein interactions, Proteomics and proteins, Translation and post-transcriptional regulation
Post-transcriptional regulation of gene expression is achieved through the control of mRNA translation, mRNA stability and subcellular mRNA localization. Post-transcriptional regulation is mediated by RNA-binding proteins and regulatory RNAs that recognize specific sequences within target transcripts. We use both Drosophila as a model to study the mechanisms that underlie post-transcriptional regulation.
Courses taught
- BCH242Y, Post-Transcriptional Regulatory Mechanisms
Cross-affiliations
- Department of Biochemistry, University of Toronto