Assistant Professor

Hartland Jackson

Molecular Genetics

PhD

Location
Lunenfeld-Tanenbaum Research Institute
Address
600 University Avenue, Room 881, Toronto, Ontario Canada M5G 1X5
Research Interests
Cancer, Cell biology, Functional genomics and systems biology, Mouse models, Imaging and microscopy, Single cell and spatial biology

The Jackson lab strives to understand tissues and tumours as the integrated outcome of their single-cell components. To do so, they utilize multiplexed imaging to simultaneously quantify single-cell phenotypes and markers of their functional state, as well as their interactions, overall organization, and contribution to tissue architecture. These methods facilitate spatially-resolved screening of distinct clones in mouse models of disease and the identification of biomarkers associated with clinical outcomes in biobanked patient tissues.

Research efforts are focused on identifying and targeting the multi-cellular tumour microenvironments that drive disease progression and therapeutic resistance in cancers of the breast and other epithelial tissues.

Awards

  • Canada Research Chair (Tier II) in Systems Pathology

Cross-affiliations

  • Ontario Institute for Cancer Research
  • Lunenfeld-Tanenbaum Research Institute