Faculty Directory
Our Faculty has grown to over 100 exceptional researchers focused in a variety of research specialties
Role of RNA-binding proteins in post-transcriptional regulation of gene expression in development and disease.
Mechanism and function of non-coding small RNA in Mycobacterium tuberculosis; Immune mechanisms of protection against MTB and vaccine development.
We study regulatory functions of the non-coding genome by focusing on lncRNAs, inter-chromosomal contacts, and genome organization.
We study new innate immune systems that we have discovered to prevent the pathogenic over proliferation of an RNA virus that infects budding yeast.
We develop and apply genome-scale perturbation technologies to explore genotype-phenotype relationships in human and mouse cells for target discovery.
Our research focuses on mapping metabolic rewiring using mass spectrometry to understand the functions of metabolites in diseases such as cancer.
We focus on using proteomics technologies including mass spectrometry and bioinformatics to identify and characterize proteins activated in cancers
Large-scale human genetics and massively parallel perturbation screens to study human disease.
We engineer and analyze human models of neuroinflammation in neurological disorders, using pluripotent stem cells, CRISPR, and new 3D culture methods.
The gut microbiota, bacterial pathogens and microbial evolution.
Dr. Okamoto's research focuses on understanding the molecular mechanisms that control brain functions such as learning and memory.
We use mouse models and human genetic analysis to probe the underlying molecular basis 7q11.23 copy number variation disorders.
Our laboratory focuses on studying the molecular mechanisms underlying neurodegenerative diseases with the aim of developing therapeutic approaches.
We apply genomics and systems approaches to study how pathogens interact with microbial communities and their host to cause disease.
Elucidating molecular mechanisms of disease-causing expansions of tandem repeated DNAs with the goal of therapeutically targeting this mutation.
We study the molecular mechanisms that govern centrosome-related processes i including centriole duplication, ciliogenesis, and spindle formation.
Modelling human heart development and diseases with pluripotent stem cells with the overarching goal to develop new therapies.
Epigenetic regulation of stem cells during mammalian development, and its modulation by environmental factors.
The Reimand lab focuses on computational biology and cancer research. We conduct integrative multi-omics analyses and develop computational methods.
We study the ubiquitous eukaryotic parasite microsporidia using C. elegans and a variety of techniques including genetics, genomics, and biochemistry.
Structural and biochemical characterization of Coronavirus receptor interactions, antibody-mediated neutralization, and viral evolution.
Novel mass spectrometric algorithms and methods for high throughput proteomics and metabolomics applied to precision medicine.
New Technologies to Identify Novel Drug Candidates, Novel Infectious Disease Drug Targets, C. elegans Models of Disease, Xenobiotic Response Circuitry
We take an RNA-centric approach, relying on systems biology and virology, to better understand arbovirus infection in mammalian and mosquito models.
Genome sequencing, annotation, medical interpretation and discovery. Studies of genomic architecture in autism, diagnostics and treatment.
The Schramek lab leverages functional genomics to study cancer development and to develop novel precision cancer therapies.
We use zebrafish and single cell genomics to define and examine conserved genes and enhancers that regulate heart development and disease.
The research focus of the Sicheri lab is to understand how eukaryotic signalling proteins function by visualizing and characterizing snapshots of these proteins in action.
Our research focuses on the development of new algorithms, methods and software for analyzing genome sequencing data.
We study how RNA-binding proteins and non-coding RNAs regulate gene expression in Drosophila embryos and human neurons.
The main goal of our lab is to understand how interactions among membrane proteins produce either healthy or diseased cells
The Stein lab focuses on using network and pathway-based analysis to identify common mechanisms in multiple cancer types
Teaching faculty for the MHSc in Medical Genomics program. Courses cover genomic methods and science communication, with a focus on active learning.